Vista 5 L5 is used for the vaccination of healthy cows and heifers, 6 months of age or older, prior to breeding as an aid in the reduction of abortion due to infectious bovine rhinotracheitis (IBR); as an aid in the prevention of fetal infection, including persistently infected calves caused by bovine virus diarrhea (BVD) (Types 1 & 2). In addition, it can be used as an aid in the prevention of disease caused by IBR, BVD (Type 2), and bovine respiratory syncytial virus (BRSV); as an aid in the control of disease caused by BVD (Type 1) and parainfluenza3 virus (PI3); and as an aid in preventing leptospirosis (caused by Leptospira canicola, L. grippotyphosa, L. hardjo - including the L. borgpetersenii serovar hardjo bovis, L. icterohaemorrhagiae, and L. pomona) and as an aid in prevention of urinary shedding of L. hardjo organisms.